溶质载体蛋白家族47成员A2抗体
规格：1mg/1ml
英文名： SLC47A2
别名： H(+)/organic cation antiporter kidney-specific; H+/organic cation antiporter; hMATE-2; Kidney-specific H(+)/organic cation antiporter; MATE-2; MATE2 B; MATE2 K; MATE2K; Multidrug and toxin extrusion 2
分子量： 61kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC47A2
交叉反应：Human, Mouse, Rabbit,
细胞定位：细胞膜
溶质载体蛋白家族47成员A2抗体产品介绍：background: This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Function: Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium 溶质载体蛋白家族47成员A2抗体(MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes. Subcellular Location: Cell membrane. Localized at the brush border membranes of the proximal tubules. Tissue Specificity: Isoform 3 is predominantly expressed in kidney. 溶质载体蛋白家族47成员A2抗体Isoform 6 is expressed in brain. Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. Database links: Entrez Gene: 146802 Human Omim: 609833 Human SwissProt: Q86VL8 Human Unigene: 126830 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产溶质载体蛋白家族47成员A2抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid