溶质载体蛋白家族47成员A1抗体
规格:1mg/1ml
英文名: SLC47A1
别名: 1A1; AIM 1; AIM1; MATP; Melanoma antigen AIM1; Membrane associated transporter; Membrane associated transporter protein; Membrane-associated transporter protein; Protein AIM 1; Protein AIM-1; Protein
分子量: 62kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC47A1
交叉反应:Human, Mouse, Rat, Rabbit,
细胞定位:细胞膜
溶质载体蛋白家族47成员A1抗体产品介绍:background: This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008] Function: Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely溶质载体蛋白家族47成员A1抗体 used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes. Subcellular Location: Cell membrane. Predominantly localized at the plasma membrane but also found in intracellular organelles. Tissue Specificity: Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes). Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. Database links: Entrez 溶质载体蛋白家族47成员A1抗体Gene: 55244 Human Omim: 609832 Human SwissProt: Q96FL8 Human Unigene: 232054 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶质载体蛋白家族47成员A1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid