PARC蛋白抗体
规格:1mg/1ml
英文名: PARC
别名: CUL-9; Cul9; CUL9_HUMAN; Cullin-9; DKFZp686G1042; DKFZp686P2024; H7AP1; KIAA0708; OTTHUMP; p53 associated parkin like cytoplasmic protein; p53-associated parkin-like cytoplasmic protein; PA
分子量: 281kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PARC
交叉反应:Human, Mouse,
细胞定位:细胞浆
PARC蛋白抗体产品介绍:Function: Cytoplasmic anchor protein in p53-associated protein complex. Regulates the subcellular localization of p53 and subsequent function. Seems to be part of an atypical cullin-RING-based E3 ubiquitin-protein ligase complex. In vitro, complexes of CUL9/PARC with either CUL7 or TP53 contain E3 ubiquitin-protein ligase activity. Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitously expressed in all tissues with highest expression in testis brain and kidney. Post-translational modifications: In vitro, PARC蛋白抗体self-ubiquitination in the presence of E1, E2 and ubiquitin. Neddylated. Similarity: Belongs to the cullin family. Contains 1 DOC domain. Contains 1 IBR-type zinc finger. Contains 2 RING-type zinc fingers. Database links: Entrez Gene: 23113 Human Entrez Gene:PARC蛋白抗体 78309 Mouse Omim: 607489 Human SwissProt: Q8IWT3 Human SwissProt: Q80TT8 Mouse Unigene: 485434 Human Unigene: 329076 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PARC蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid