溶质载体蛋白家族3成员A1抗体
规格:1mg/1ml
英文名: SLC3A1
别名: +)-type amino acid transport protein; amino acid transporter 1; ATR1; B(0; B(0,+)-type amino acid transport protein; CSNU1; D2H; FLJ34681; NBAT; Neutral and basic amino acid transport protein rBAT; RB
分子量: 79kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC3A1
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
溶质载体蛋白家族3成员A1抗体产品介绍:background: This gene encodes a type II membrane glycoprotein which is one of the components of the renal amino acid transporter which transports neutral and basic amino acids in the renal tubule and intestinal tract. Mutations and deletions in this gene are associated with cystinuria. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] Function: Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption 溶质载体蛋白家族3成员A1抗体of cystine in the kidney tubule. Subcellular Location: Membrane. Tissue Specificity: Expressed in the brush border membrane in the kidney (at protein level). Predominantly expressed in the kidney, small intestine and pancreas. Weakly expressed in liver. DISEASE: Cystinuria. Hypotonia-cystinuria syndrome. Database links: Entrez Gene: 6519 Human Entrez Gene: 20532 Mouse Entrez Gene: 29484溶质载体蛋白家族3成员A1抗体 Rat SwissProt: Q07837 Human SwissProt: Q91WV7 Mouse SwissProt: Q64319 Rat Unigene: 112916 Human Unigene: 227176 Mouse Unigene: 461481 Mouse Unigene: 11196 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶质载体蛋白家族3成员A1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid