尾侧型同源转录因子2/3抗体
规格:1mg/1ml
英文名: CDX2+3
别名: Caudal type homeo box 2; Caudal type homeo box transcription factor 2; Caudal type homeobox 2; Caudal type homeobox protein 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CDX2/3
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow, Horse,
细胞定位:细胞核
尾侧型同源转录因子2/3抗体产品介绍:background: This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]. Function: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylation of Ser-60 mediates the transactivation capacity.尾侧型同源转录因子2/3抗体 Similarity: Belongs to the Caudal homeobox family. Contains 1 homeobox DNA-binding domain. Gene ID: 1045 Database links: Entrez Gene: 1045 Human Entrez Gene: 12591 Mouse Entrez Gene: 66019 Rat Omim: 600297 Human 尾侧型同源转录因子2/3抗体SwissProt: Q99626 Human SwissProt: P43241 Mouse Unigene: 174249 Human Unigene: 20358 Mouse Unigene: 64495 Ra Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
尾侧型同源转录因子2/3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 发育生物学 信号转导 干细胞 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid