环指蛋白34抗体
规格：1mg/1ml
英文名： RNF34
别名： Caspase regulator CARP1; CARP 1; CARP-1; CARP1; Caspase regulator CARP1; Caspases-8 and -10-associated RING finger protein 1; E3 ubiquitin-protein ligase RNF34; FYVE-RING finger protein Momo; hRFI; Hu
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RNF34
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核 细胞膜
环指蛋白34抗体产品介绍：background: Has E3 ubiquitin-protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Protects cells against apoptosis induced by TNF. Binds phosphatidylinositol-5-phosphate and phosphatidylinositol-3-phosphate. Function: Has E3 ubiquitin-protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Protects cells against apoptosis induced by TNF. Binds phosphatidylinositol 5-phosphate and phosphatidylinositol 3-phosphate. Subunit: Interacts with DNAJA3 (Potential). Interacts with CASP8 and CASP10. Subcellular Location: Nucleus speckle. Endomembrane system; Peripheral membrane protein. Tissue Specificity: Ubiquitous. Detected in heart, brain, liver, skeletal muscle, kidney, pancreas, spleen,环指蛋白34抗体 thymus, prostate, testis, ovary, colon and leukocytes. Post-translational modifications: Auto-ubiquitinated (in vitro) (By similarity). Proteolytically cleaved by caspases upon induction of apoptosis by TNF. Similarity: Contains 1 FYVE-type zinc finger. Contains 1 RING-type zinc finger. Contains 2 SAP domains. Gene ID: 80196 Database links: Entrez Gene: 80196 Human Entrez Gene: 80751 Mouse Entrez Gene: 282845 Rat环指蛋白34抗体 Omim: 608299 Human SwissProt: Q5E9J6 Cow SwissProt: Q969K3 Human SwissProt: Q99KR6 Mouse SwissProt: Q6AYH3 Rat Unigene: 292804 Human Unigene: 388529 Mouse Unigene: 14904 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
环指蛋白34抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid