环指蛋白19B抗体
规格:1mg/1ml
英文名: RNF19B
别名: E3 ubiquitin-protein ligase RNF19B; IBR domain containing 3; IBR domain-containing protein 3; IBRDC3; Natural killer lytic-associated molecule; NKLAM; RING finger protein 19B; RN19B_HUMAN; rnf19b.
分子量: 78kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RNF19B
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞浆 细胞膜
环指蛋白19B抗体产品介绍:background: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. Function: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. Subunit: Interacts with UBE2L3, UBE2L6 and UCKL1. Subcellular Location: 环指蛋白19B抗体Cytoplasmic granule membrane. Tissue Specificity: Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells. Present in natural killer cells Similarity: Belongs to the RBR family. RNF19 subfamily. Contains 1 IBR-type zinc finger. Contains 2环指蛋白19B抗体 RING-type zinc fingers. Gene ID: 127544 Database links: Entrez Gene: 127544 Human Omim: 610872 Human SwissProt: Q6ZMZ0 Human Unigene: 591504 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
环指蛋白19B抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 t-**细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid