胱抑素8/半胱氨酸蛋白酶抑制剂8抗体
规格：1mg/1ml
英文名： CST8
别名： CRES; CST 8; Cst8; CST8_HUMAN; cystatin 8 (cystatin related epididymal specific); Cystatin 8; Cystatin related epididymal specific; Cystatin related epididymal specific protein; Cystatin related epidi
分子量： 14kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CST8/Cys
交叉反应：Human, Mouse, Rat, Dog,
细胞定位：分泌型蛋白
胱抑素8/半胱氨酸蛋白酶抑制剂8抗体产品介绍：background: The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes. The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily. CRES proteins lack two of the three consensus sites necessary for the cystatin inhibition of C1 cysteine proteases. They are also preferentially expressed in postmeiotic germ cells, the proximal caput epididymidis, and anterior pituitary gonadotrophs. Therefore, CRES proteins may perform unique and tissue-specific functions in the reproductive and neuroendocrine systems. As a member of the CRES subfamily, Cystatin胱抑素8/半胱氨酸蛋白酶抑制剂8抗体 8 is a 142 amino acid protein that is expressed in the proximal caput region of the epididymis, where it performs a specialized role during sperm development and maturation. Function: Performs a specialized role during sperm development and maturation. Subcellular Location: Secreted. Tissue Specificity: Proximal caput region of the epididymis. Lower expression in the testis. Within the testis it is localized to the elongating spermatids, whereas within the epididymis it is exclusively synthesized by the proximal caput epithelium. Similarity: Belongs to the胱抑素8/半胱氨酸蛋白酶抑制剂8抗体 cystatin family. Gene ID: 10047 Database links: Entrez Gene: 10047 Human Entrez Gene: 13012 Mouse Entrez Gene: 29679 Rat Omim: 608683 Human SwissProt: O60676 Human SwissProt: P32766 Mouse SwissProt: O88969 Rat Unigene: 121602 Human Unigene: 20435 Mouse Unigene: 18514 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胱抑素8/半胱氨酸蛋白酶抑制剂8抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid