胱抑素9/半胱氨酸蛋白酶抑制剂9抗体
规格：1mg/1ml
英文名： CST9
别名： M12; CLM; Cresp; Cst9; CST9_HUMAN; Cystatin 9 (testatin); Cystatin like molecule; Cystatin-9; Cystatin-like molecule; Testatin.
分子量： 15kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CST9/Cys
交叉反应：Human,
细胞定位：细胞浆 分泌型蛋白
胱抑素9/半胱氨酸蛋白酶抑制剂9抗体产品介绍：background: The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes. The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily. CRES proteins lack two of the three consensus sites necessary for the cystatin inhibition of C1 cysteine proteases. Due to their expression patterns, it is likely that CRES proteins may perform unique and tissue-specific functions in the reproductive and neuroendocrine systems.胱抑素9/半胱氨酸蛋白酶抑制剂9抗体 As a member of the CRES subfamily, Cystatin 9, also designated CLM, is a 159 amino acid protein that is expressed in heart, placenta, lung, liver, skeletal muscle and pancreas. Cystatin 9 is thought to play a role in hematopoietic differentiation or inflammation. It has also been shown to be upregulated by LPS in some cancer cell lines, such as promyelocytic leukemia (HL-60) and myelomonocytic leukemia. Function: May play a role in hematopoietic differentiation or inflammation. Subcellular Location: Secreted. May be targeted through the Golgi via the secretory pathway. Tissue Specificity: Expressed in heart, placenta, lung, liver, skeletal muscle and pancreas. Not expressed in brain.胱抑素9/半胱氨酸蛋白酶抑制剂9抗体Barely expressed in tumor cell lines except for breast adenocarcinoma MCF-7 cells and U251 cells. Similarity: Belongs to the cystatin family. Gene ID: 128822 Database links: Entrez Gene: 128822 Human SwissProt: Q5W186 Human Unigene: 698020 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胱抑素9/半胱氨酸蛋白酶抑制剂9抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid