胱抑素S/半胱氨酸蛋白酶抑制剂S抗体
规格:1mg/1ml
英文名: Cystatin S
别名: Cst4; Cystatin 4; Cystatin S precursor; Cystatin SA III; Cystatin-4; Cystatin-S; Cystatin-SA-III; CYTS_HUMAN; MGC71923; Salivary acidic protein 1.
分子量: 16kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Cystatin
交叉反应:Human,
细胞定位:分泌型蛋白
胱抑素S/半胱氨酸蛋白酶抑制剂S抗体产品介绍:background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function. [provided by 胱抑素S/半胱氨酸蛋白酶抑制剂S抗体RefSeq, Jul2008]. Function: This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively. Subcellular Location: Secreted. Tissue Specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid. Post-translational modifications: Phosphorylated at both its N- and C-terminal regions. Similarity: Belongs to the cystatin family. Gene ID:胱抑素S/半胱氨酸蛋白酶抑制剂S抗体 1472 Database links: Entrez Gene: 1472 Human Omim: 123857 Human SwissProt: P01036 Human Unigene: 654549 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胱抑素S/半胱氨酸蛋白酶抑制剂S抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid