环指蛋白14抗体
规格：1mg/1ml
英文名： RNF14
别名： Androgen receptor associated protein 54; Androgen receptor-associated protein 54; ARA 54; ARA54; E3 ubiquitin protein ligase RNF14; E3 ubiquitin-protein ligase RNF14; FLJ26004; HFB 30; HFB30; HRIHFB20
分子量： 54kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RNF14
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
环指蛋白14抗体产品介绍：background: Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription. Function: Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a环指蛋白14抗体role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription. Subunit: Interacts with the ubiquitin-conjugating enzymes UBE2E1 and UBE2E2. Interacts with AR/androgen receptor; testosterone- and RNF6-regulated it promotes AR transcriptional activity. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Widely expressed. Post-translational modifications: RING-type zinc finger-dependent and UBE2E2-dependent autoubiquitination. [SIMILARITY] Similarity: Belongs to the RBR family. RNF14 subfamily. Contains 1 IBR-type 环指蛋白14抗体zinc finger. Contains 2 RING-type zinc fingers. Contains 1 RWD domain. Gene ID: 9604 Database links: Entrez Gene: 9604 Human Entrez Gene: 56736 Mouse Entrez Gene: 619577 Rat Omim: 605675 Human SwissProt: Q9UBS8 Human SwissProt: Q9JI90 Mouse Unigene: 483616 Human Unigene: 228903 Mouse Unigene: 115357 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
环指蛋白14抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid