**球蛋白超家族成员3抗体
规格：1mg/1ml
英文名： IGSF3
别名： EWI 3; EWI3; Glu Trp Ile EWI motif containing protein 3; Immunoglobin superfamily member 3; Immunoglobulin superfamily member 3; KIAA0466; MGC117164; V8 antibody; IGSF3_HUMAN.
分子量： 133kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IGSF3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
**球蛋白超家族成员3抗体细胞定位：细胞膜
产品介绍：background: IGSF3, also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and**球蛋白超家族成员3抗体 CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function. Based on its subcellular localization and the presence of the eight Ig domains, IGSF3 is hypothesized to function as a surface receptor or as a cell adhesion molecule. Subcellular Location: Membrane; Single-pass type I membrane protein Tissue Specificity: It is expressed in**球蛋白超家族成员3抗体 a wide range of tissues with high expression in placenta, kidney and lung. Similarity: Contains 8 Ig-like C2-type (immunoglobulin-like) domains. Gene ID: 3321 Database links: Entrez Gene: 3321 Human Entrez Gene: 78908 Mouse Entrez Gene: 295325 Rat Omim: 603491 Human SwissProt: O75054 Human SwissProt: Q6ZQA6 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
**球蛋白超家族成员3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞粘附分子 细胞表面分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid