**球蛋白超家族成员6抗体
规格：1mg/1ml
英文名： IGSF6
别名： DORA; Immunoglobulin superfamily member 6; IGSF6_HUMAN.
分子量： 24kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IGSF6
交叉反应：Human,
细胞定位：细胞膜
**球蛋白超家族成员6抗体产品介绍：background: Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF6 (immunoglobulin superfamily, member 6), also known as DORA, is a novel 241 amino acid single-pass type I membrane protein that contains one Ig-like C2-type (immunoglobulin-like) domain. Expressed in spleen, dendritic cells, peripheral blood lymphocytes and lymph node, IGSF6 is induced by TNF?and GM-CSF in dendritic cells and downregulated by ionomycin and PMA in monocytes. IGSF6 may function as a co-receptor in the antigen uptake complex or dendritic cell recirculation**球蛋白超家族成员6抗体 and is encoded by a gene located on human chromosome 16p12.2, a locus associated with inflammatory bowel disease. Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Tissue Specificity: Expressed in peripheral blood lymphocytes, spleen and lymph node, with low levels in thymus, bone marrow and fetal liver. No expression in non-immune tissues. Similarity: Contains 1 Ig-like**球蛋白超家族成员6抗体 C2-type (immunoglobulin-like) domain. Gene ID: 10261 Database links: Entrez Gene: 10261 Human Omim: 606222 Human SwissProt: O95976 Human Unigene: 530902 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
**球蛋白超家族成员6抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞表面分子
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid