**球蛋白超家族成员10抗体
规格：1mg/1ml
英文名： IGSF10
别名： Adlican2; Calvaria mechanical force protein 608; CMF608; IGS10_HUMAN; IgSF10; Immunoglobulin superfamily member 10.
分子量： 288kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IGSF10
交叉反应：Human,
细胞定位：分泌型蛋白
产**球蛋白超家族成员10抗体品介绍：background: Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF10 (immunoglobulin superfamily, member 10), also known as Calvaria mechanical force protein 608 (CMF608), is a 2,623 amino acid secreted protein that contains an N-terminal signal peptide, six leucine-rich repeats (LRRs), and 12 immunoglobulin-like repeats. IGSF10 exists as multiple alternatively spliced isoforms, and is expressed in bone. Specifically, expression of IGSF10 is limited to mesenchymal osteochondroprogenitors with fibroblast-like morphology, where it is thought to be involved in the maintenance of the osteochondroprogenitor cells pool and its down-regulation precedes terminal differentiation. The gene encoding IGSF10 maps to **球蛋白超家族成员10抗体chromosome 3, which comprises over 1,100 genes that include a chemokine receptor gene cluster as well as a variety of human cancer related loci. Function: May be involved in the maintenance of osteochondroprogenitor cells pool (By similarity). Subcellular Location: Secreted Similarity: Contains 12 Ig-like C2-type (immunoglobulin-like) domains. Contains 6 LRR (leucine-rich) repeats. Contains **球蛋白超家族成员10抗体1 LRRCT domain. Contains 1 LRRNT domain. Gene ID: 285313 Database links: Entrez Gene: 285313 Human SwissProt: Q6WRI0 Human Unigene: 58561 Human Unigene: 727746 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产**球蛋白超家族成员10抗体品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞周期蛋白 细胞表面分子 细胞分化 细胞骨架 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid