大脑和睾丸特异性**球蛋白超家族成员11抗体
规格：1mg/1ml
英文名： IGSF11
别名： brain and testis specific immunoglobin superfamily protein; BTIGSF; CXADR like 1; CXADRL1; Igsf13; immunoglobulin superfamily member 11; Immunoglobulin superfamily member 11 precursor; MGC35227; V set
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IGSF11
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
大脑和睾丸特异性**球蛋白超家族成员11抗体产品介绍：background: IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be大脑和睾丸特异性**球蛋白超家族成员11抗体 involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy. Function: Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth. Subcellular Location: Cell Membrane, Single-pass type I membrane protein. Tissue Specificity: bundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle. Post-translational modifications: N-glycosylated (By similarity).大脑和睾丸特异性**球蛋白超家族成员11抗体 Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Gene ID: 152404 Database links: Entrez Gene: 152404 Human Entrez Gene: 207683 Mouse Entrez Gene: 303926 Rat Omim: 608351 Human SwissProt: Cow SwissProt: Q5DX21 Human SwissProt: P0C673 Mouse SwissProt: Q5U2P2 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产大脑和睾丸特异性**球蛋白超家族成员11抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 细胞膜受体 细胞表面分子 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid