含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族7抗体
规格：1mg/1ml
英文名： ASB7
别名： Ankyrin repeat and SOCS box containing protein 7; ASB 7; ASB-7; ASB7_HUMAN.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ASB7
交叉反应：Human, Mouse, Rat, Chicken, Horse, Sheep,
细胞定位：
含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族7抗体产品介绍：background: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-7 (ankyrin repeat and SOCS box-containing 7) is a 318 amino acid protein that contains one SOCS含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族7抗体 box domain and seven ANK repeats and belongs to the ASB family. Existing as multiple alternatively spliced isoforms, ASB-7 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族7抗体 and subsequent proteasomal degradation of target proteins (By similarity). Subunit: Interacts with CUL5 and RNF7. Similarity: Contains 7 ANK repeats. Contains 1 SOCS box domain. Database links: UniProtKB/Swiss-Prot: Q9H672.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid