含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族13抗体
规格：1mg/1ml
英文名： ASB13
别名： Ankyrin repeat and SOCS box containing 13; Ankyrin repeat and SOCS box containing protein 13; Ankyrin repeat and SOCS box protein 13; Ankyrin repeat domain containing SOCS box protein Asb 13; Ankyrin
分子量： 30kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ASB13
交叉反应：Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit,
细胞定位：
含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族13抗体产品介绍：background: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-13 (ankyrin repeat and SOCS box-containing 13) is a 278 amino acid member of the ASB family that 含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族13抗体contains one SOCS box domain and six ANK repeats. Existing as multiple isoforms, ASB-13 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. Function: May be a substrate-recognition含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族13抗体 component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Similarity: Contains 6 ANK repeats. Contains 1 SOCS box domain. Database links: UniProtKB/Swiss-Prot: Q8WXK3.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族13抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid