G蛋白偶联受体TAS1R3抗体
规格:1mg/1ml
英文名: TAS1R3
别名: GPCR TAS1R3; Sweet taste receptor T1R3; T1 R3; T1R 3; T1R3; TAS1 R3; TAS1R 3; TAS1R3; Taste receptor type 1 member 3; Taste receptor type 1 member 3 precursor; TR 3; TR3; TS1R3_HUMAN; .
分子量: 92kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TAS1R3
交叉反应:Human, Mouse, Rat, Dog, Cow,
细胞定位:细胞膜
G蛋白偶联受体TAS1R3抗体产品介绍:background: The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners (Max et al., 2001 [PubMed 11326277]).[supplied by OMIM, Jan 2010]. Function: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between G蛋白偶联受体TAS1R3抗体species can significantly influence the selectivity and specificity of taste responses. Subunit: Forms homodimers or heterodimers with TAS1R1 and TAS1R2. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in vascular endothelium. Post-translational modifications: Phosphorylated by FER and other protein-tyrosine kinases. Phosphorylated at Ser-288 by PAK7/PAK5.G蛋白偶联受体TAS1R3抗体 Dephosphorylated by PTPRJ. Similarity: Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily. Database links: UniProtKB/Swiss-Prot: Q7RTX0.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体TAS1R3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:20-100 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid