肿瘤/睾丸抗原2.2/睾丸抗原2.3抗体
规格：1mg/1ml
英文名： BAGE2 + BAGE3
别名： B melanoma antigen 2; B melanoma antigen family, member 2; Cancer/testis antigen 2.2; CT2.2; BAGE2_HUMAN; B melanoma antigen family member 3; B melanoma antigen 3; BAGE3; BAGE3_HUMAN; Cancer/testis an
分子量： 10kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BAGE2 an
交叉反应：Human,
细胞定位：分泌型蛋白
肿瘤/睾丸抗原2.2/睾丸抗原2.3抗体产品介绍：background: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as肿瘤/睾丸抗原2.2/睾丸抗原2.3抗体 Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis. Function: Unknown.肿瘤/睾丸抗原2.2/睾丸抗原2.3抗体 Candidate gene encoding tumor antigens. Subcellular Location: Secreted. Tissue Specificity: Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas. Similarity: Belongs to the BAGE family. Gene ID: 85319 Database links: Entrez Gene: 85319 Human SwissProt: Q86Y30 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤/睾丸抗原2.2/睾丸抗原2.3抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid