肿瘤/睾丸抗原2.3抗体
规格：1mg/1ml
英文名： BAGE3
别名： B melanoma antigen family member 3; B melanoma antigen 3; BAGE3; BAGE3_HUMAN; Cancer/testis antigen 2.3; Cancer/testis antigen family 2 member 3; CT2.3.
分子量： 10kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BAGE3
交叉反应：Human,
细胞定位：分泌型蛋白
肿瘤/睾丸抗原2.3抗体产品介绍：background: Unknown. Candidate gene encoding tumor antigens. Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22%肿瘤/睾丸抗原2.3抗体 of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis. Function: Unknown. Candidate gene encoding tumor antigens. Subcellular Location: Secreted Tissue Specificity: Not expressed in normal tissues except in testis肿瘤/睾丸抗原2.3抗体 Expressed in melanoma, bladder and lung carcinomas. Similarity: Belongs to the BAGE family. Database links: UniProtKB/Swiss-Prot: Q86Y29.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤/睾丸抗原2.3抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid