轴突蛋白3 beta抗体
规格：1mg/1ml
英文名： Neurexin-3-beta
别名： Neurexin-3-beta; Neurexin III-beta; Neurexin-3-beta, soluble form; NRX3B_HUMAN; NRXN3; KIAA0743.
分子量： 65kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Neurexin
交叉反应：Human, Mouse, Chicken, Cow,
细胞定位：细胞膜
轴突蛋白3 beta抗体产品介绍：background: This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012] Function: Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis. Subunit: The cytoplasmic C-terminal region binds to CASK. Binds to neuroligins NLGN1, NLGN2 and NLGN3. Subcellular Location: Membrane; Single-pass type I membrane protein 轴突蛋白3 beta抗体(Potential). Tissue Specificity: Expressed in the blood vessel walls (at protein level). Post-translational modifications: Proccessed by alpha-secretase leading to the formation of an extracellular soluble protein as well as a C-terminal membrane-embedded fragment (CTF). Proteolysis of these CTFs by gamma-secretase releases intracellular domains (ICDs) and extracellular peptides. Similarity: Belongs to the neurexin family. Contains 1 laminin G-like domain. Gene ID: 9369 Database links: Entrez Gene: 9369 Human Entrez Gene: 18191 Mouse Entrez Gene: 116508 Rat轴突蛋白3 beta抗体 Omim: 600567 Human SwissProt: Q9HDB5 Human SwissProt: Q9Y4C0 Human SwissProt: Q6P9K9 Mouse SwissProt: Q8C985 Mouse SwissProt: Q8CCT8 Mouse SwissProt: Q07310 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
轴突蛋白3 beta抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid