异质核糖核蛋白U2样蛋白抗体
规格：1mg/1ml
英文名： HORMAD2
别名： HNRNPUL2; HORMA domain containing 2; DKFZp762N1910; Heterogeneous nuclear ribonucleoprotein U like 2; Heterogeneous nuclear ribonucleoprotein U like protein 2; Heterogeneous nuclear ribonucleoprotein
分子量： 85kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HORMAD2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞核
异质核糖核蛋白U2样蛋白抗体产品介绍：background: HORMAD2 is a 307 amino acid protein that contains one HORMA domain and is expressed in brain, testis and liver with lower levels present in kidney. The gene encoding HORMAD2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. Subunit: Binds to MLF1 and retains it in the nucleus. 异质核糖核蛋白U2样蛋白抗体Subcellular Location: Nucleus. Chromosome. Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the male and female prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. Tissue Specificity: Expressed in testis, liver and brain, and at lower levels in kidney Similarity: Contains 1 B30.2/SPRY domain. Contains 1 SAP domain. 异质核糖核蛋白U2样蛋白抗体Database links: Entrez Gene: 150280 Human Entrez Gene: 75828 Mouse Entrez Gene: 498400 Rat SwissProt: Q8N7B1 Human SwissProt: Q5SQP1 Mouse Unigene: 120391 Human Unigene: 159592 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
异质核糖核蛋白U2样蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞周期蛋白 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid