肝癌衍生生长因子2抗体
规格：1mg/1ml
英文名： HRP2
别名： HDGF-2; Hdgfrp2; HDGR2_HUMAN; Hepatoma-derived growth factor 2; Hepatoma-derived growth factor; Hepatoma-derived growth factor-related protein 2; heptoma derived growth factor related protein 2; HRP-2
分子量： 74kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HRP2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
细胞定位：
肝癌衍生生长因子2抗体产品介绍：background: Hepatoma Derived Growth Factor (HDGF) is the original member of a family of polypeptides designated HDGF-related proteins (HRPs). HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. This nuclear targeted vascular smooth muscle cell mitogen (VSM) is a heparin-binding protein that is highly expressed in tumor cells where it stimulates proliferation. HDGF is also reported to be involved in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. During development, HDGF expression is high in the nucleus and cytoplasm of smooth muscle and endothelial cells. The HRP (HDGF related proteins) family contains four proteins, HRP-1, HRP-2, HRP-3 and HRP-4. HRP-1 and HRP-4 are only expressed in testis while HRP-2肝癌衍生生长因子2抗体 is widely expressed in different tissues. HRP-3 can solely be found in the nervous system. Specifically it is strongly expressed in bulbus, olfactorius, piriform cotrex and amygdala complex while HRP-2 in brain is located in the the thalamus, prefrontal and parietal cortex, neurohypophysis, and the cerebellum. In the central nervous system, HRP proteins are play a role in neuron proliferation and cell survival. Subunit: May interact with trimethylated histone H3 (H3K79me3) Subcellular Location: . Post-translational modifications: Phosphorylated upon DNA damage, probably by肝癌衍生生长因子2抗体 ATM or ATR. Similarity: Belongs to the HDGF family. Contains 1 PWWP domain. Database links: Entrez Gene: 84717 Human Entrez Gene: 15193 Mouse Entrez Gene: 171073 Rat SwissProt: Q7Z4V5 Human SwissProt: Q3UMU9 Mouse SwissProt: Q925G1 Rat Unigene: 43071 Human Unigene: 279188 Mouse Unigene: 29462 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肝癌衍生生长因子2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid