瞬时受体电位离子通道蛋白3抗体
规格：1mg/1ml
英文名： TRPM3
别名： GON 2; GON2; Long transient receptor potential channel 3; LTRPC 3; LTRPC3; Melastatin 2; Melastatin2; MLSN 2; MLSN2; Transient receptor potential cation channel subfamily M member 3; transient recepto
分子量： 197kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TRPM3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
瞬时受体电位离子通道蛋白3抗体产品介绍：background: The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]. Function: Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed primarily in the kidney and, at lower levels, in brain, testis, ovary, pancreas and瞬时受体电位离子通道蛋白3抗体 spinal cord. Expression in the brain and kidney was determined at protein level. In the kidney, expressed predominantly in the collecting tubular epithelium in the medulla, medullary rays, and periglomerular regions; in the brain, highest levels are found in the cerebellum, choroid plexus, the locus coeruleus, the posterior thalamus and the substantia nigra. Down-regulated in renal tumors compared to normal kidney. Similarity: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM3 sub-subfamily. Database links: Entrez Gene: 476326 Dog瞬时受体电位离子通道蛋白3抗体 Entrez Gene: 80036 Human Entrez Gene: 226025 Mouse Entrez Gene: 309407 Rat Omim: 608961 Human SwissProt: Q9HCF6 Human SwissProt: Q5F4S6 Mouse Unigene: 47288 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
瞬时受体电位离子通道蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 信号转导 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid
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