Dermokine β蛋白抗体
规格：1mg/1ml
英文名： Dermokine beta
别名： Dermokineβ; Dermokine-β; DMKN;Dermokine beta; Dermokine delta 1; Dermokine delta 5a; Dermokine delta 5b; Dermokine gamma 1; Dermokine gamma 2; UNQ729; ZD52F10 protein; Epidermis-specific secreted prot
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Dermokin
交叉反应：Human,
细胞定位：分泌型蛋白
Dermokine β蛋白抗体产品介绍：background: Dermokine, also known as DMKN, ZD52F10 or UNQ729, is a 476 amino acid secreted protein that belongs to the dermokine family and exists as 15 alternatively spliced isoforms, the most notable of which are designated å and ∫. Existing as a homooligomer that can either homodimerize or homotrimerize, Dermokine is expressed in the epidermis, as well as in the epithelia of the lung and small intestine where it is thought to function as a regulator of keratinocyte differentiation, possibly playing a role in inflammatory responses. The gene encoding Dermokine maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number Dermokine β蛋白抗体of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Function: May act as a soluble regulator of keratinocyte differentiation (Potential). Subunit: Homooligomer. Seems to be able to homodimerize and homotrimerize. Subcellular Location: Secreted. Tissue Specificity: Expressed in epidermis; in the spinous and granular layers and in placenta. Also found in the epithelia of the small intestine, macrophages of the lung and endothelial cells of the lung. Dermokine β蛋白抗体Isoform 15 is expressed in epidermis and placenta. Isoform 1 is expressed in epidermis. Post-translational modifications: O-glycosylated. Similarity: Belongs to the dermokine family. Database links: Entrez Gene: 93099 Human SwissProt: Q6E0U4 Human SwissProt: Q96EW8 Human Unigene: 417795 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Dermokine β蛋白抗体产品应用：ELISA=1:500-1000 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid