前列腺癌激活蛋白抗体
规格：1mg/1ml
英文名： PDZK3
别名： Activated in prostate cancer protein; AIPC; KIAA0300; Likely ortholog of rat plakophilin related armadillo repeat protein interacting PDZ protein antibody PAPIN; PDZ domain containing 2; PDZ domain co
分子量： 310kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PDZK3
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位：细胞核 细胞浆 分泌型蛋白
前列腺癌激活蛋白抗体产品介绍：background: Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. PDZK3 contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, the PDZK3 gene is upregulated in primary prostate tumors and may be involved in the early stages of前列腺癌激活蛋白抗体 prostate tumorigenesis. Subunit: Interacts with SCN10A, CTNND2 and PKP4 (By similarity). Subcellular Location: Cytoplasmic, Endoplasmic reticulum, Nuclear and Secreted Tissue Specificity: Isoform 2 is expressed (at protein level) in prostate and many prostate tumors. Post-translational modifications: A secreted form is produced by caspase-mediated proteolytic cleavage (By similarity). Similarity: Contains 6 PDZ 前列腺癌激活蛋白抗体(DHR) domains. Database links: Entrez Gene: 23037 Human Entrez Gene: 68070 Mouse Entrez Gene: 65034 Rat Omim: 610697 Human SwissProt: O15018 Human SwissProt: Q9QZR8 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产前列腺癌激活蛋白抗体品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid