癌/睾丸抗原抗体86抗体
规格：1mg/1ml
英文名： OIP-5/CT86
别名： 5730547N13Rik; Cancer/testis antigen 86; CT 86; CT86; hMIS18beta; LAP2alpha interactor 25; LINT 25; LINT25; MIS18B; MIS18beta; MS18B_HUMAN; OIP 5; OIP-5; OIP5; Opa interacting protein 5; Opa-interacti
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human OIP-5
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核 细胞浆
癌/睾丸抗原抗体86抗体产品介绍：background: OIP5 is a 229 amino acid nuclear protein that is required for chromosome segregation during mitosis. OIP5 exists as a homodimer but can also heterodimerize with FASP1 (FAPP1-associated protein 1). Essential for the recruitment of CENP-A (centromere autoantigen A) to centromeres, OIP5 localizes to centromeres of interphase cells during late anaphase and G1. The gene encoding OIP5 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. 癌/睾丸抗原抗体86抗体Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. Function: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. Subcellular Location: Nucleus. Chromosome. Chromosome, centromere. Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin. Gene ID: 11339 Database links: Entrez癌/睾丸抗原抗体86抗体Gene: 11339 Human Omim: 606020 Human SwissProt: O43482 Human Unigene: 661645 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
癌/睾丸抗原抗体86抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid