高迁移率家族蛋白3抗体
规格:1mg/1ml
英文名: HMG4/HMGB3
别名: High mobility group (nonhistone chromosomal) protein 4; High mobility group box 3; High mobility group protein 2a; High mobility group protein 4; High mobility group protein B3; High mobility group pr
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HMG4/HMG
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞核
高迁移率家族蛋白3抗体产品介绍:background: HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM, Mar 2008] Function: Binds preferentially 高迁移率家族蛋白3抗体single-stranded DNA and unwinds double stranded DNA. Subcellular Location: Nucleus. Chromosome. Tissue Specificity: Expressed predominantly in placenta. Similarity: Belongs to the HMGB family. Contains 2 HMG box DNA-binding domains. Gene ID: 高迁移率家族蛋白3抗体3149 Database links: Entrez Gene: 3149 Human Entrez Gene: 613729 Cow Entrez Gene: 15354 Mouse Entrez Gene: 305373 Rat Omim: 300193 Human SwissProt: Q32L31 Cow SwissProt: O15347 Human SwissProt: O54879 Mouse Unigene: 19114 Human Unigene: 336087 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
高迁移率家族蛋白3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 转录调节因子 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid