谷氧还蛋白3抗体
规格:1mg/1ml
英文名: GLRX3/TXNL2
别名: glrx3; GLRX3_HUMAN; GLRX4; Glutaredoxin 3; Glutaredoxin 4; Glutaredoxin-3; Glutaredoxin3; GRX3; GRX4; PICOT; PKC interacting cousin of thioredoxin; PKC theta interacting protein; PKC-interacting cousi
分子量: 37kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GLRX3/TX
交叉反应:Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞浆
谷氧还蛋白3抗体产品介绍:Function: Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. Subcellular Location: Cytoplasm > cell cortex. Cytoplasm > myofibril > sarcomere > Z line. Under the plasma membrane. After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area.谷氧还蛋白3抗体 In the Z line, found associated with CSRP3. Tissue Specificity: Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine. Similarity: Contains 2 glutaredoxin domains. Contains 1 thioredoxin domain. Gene ID: 511528 Database links: Entrez Gene: 511528 Cow Entrez Gene: 10539 Human Entrez Gene: 30926 Mouse谷氧还蛋白3抗体 Entrez Gene: 58815 Rat SwissProt: Q58DA7 Cow SwissProt: O76003 Human SwissProt: Q9CQM9 Mouse SwissProt: Q9JLZ1 Rat Unigene: 42644 Human Unigene: 267692 Mouse Unigene: 3578 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
谷氧还蛋白3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid