蛋白精氨酸甲基转移酶2抗体
规格：1mg/1ml
英文名： PRMT2
别名： ANM2_HUMAN; EC 2.1.1.; histone arginine N methyltransferase PRMT2; Histone-arginine N-methyltransferase PRMT2; HMT 1; HMT1 (hnRNP methyltransferase S. cerevisiae) like 1; HMT1; HMT1 hnRNP methyltransf
分子量： 49kDa
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PRMT2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
蛋白精氨酸甲基转移酶2抗体产品介绍：Function: Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation. Subunit: Self-associates. Interacts with RB1 and E2F1 (By similarity). Interacts with NCOA6 coactivator.蛋白精氨酸甲基转移酶2抗体 Interacts (via SH3 domain) with PRMT8. Interacts with AR. Interacts with NFKBIA.Interacts with ESR1, ESR2, PGR, PPARG, RARA, RXRA and THRB.Interacts with HNRNPUL1. Subcellular Location: Cytoplasm. Nucleus. Translocates from the cytoplasm to the nucleus, after hormone exposure. Tissue Specificity: Widely expressed. Highly expressed in androgen target organs such as heart, prostate, skeletal muscle, ovary and spinal cord. Similarity: Belongs to the protein arginine N-methyltransferase family. Contains 1 SH3 domain. Gene ID: 3275 Database links:蛋白精氨酸甲基转移酶2抗体 Entrez Gene: 3275 Human Entrez Gene: 15468 Mouse Entrez Gene: 499420 Rat Omim: 601961 Human SwissProt: P55345 Human SwissProt: Q9R144 Mouse Unigene: 154163 Human Unigene: 32020 Mouse Unigene: 145566 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白精氨酸甲基转移酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid