锌指蛋白ZMYM3抗体
规格:1mg/1ml
英文名: ZMYM3
别名: DXS6673E; KIAA0385; MYM; XFIM; ZFP261; Zinc finger MYM type 3; Zinc finger MYM type protein 3; Zinc finger MYM-type protein 3; Zinc finger protein 261; ZMYM 3; ZMYM3; ZMYM3_HUMAN; ZNF 261; ZNF198L2; Z
分子量: 152kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZMYM3
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, Guinea Pig, Ferret, Rhesus monkey, Gorilla, Orangutan
细胞定位:细胞核
锌指蛋白ZMYM3抗体产品介绍:background: This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010] Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. Subunit: May be a component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, KDM1A, RCOR1/CoREST, PHF21A/BHC80, ZMYM2, ZNF217锌指蛋白ZMYM3抗体 ZMYM3, GSE1 and GTF2I. Subcellular Location: Nucleus. Tissue Specificity: Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta. DISEASE: Note=A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?). Similarity: Contains 9 MYM-type zinc fingers. Gene ID: 9203 Database links: Entrez Gene: 9203 Human Entrez Gene: 56364 Mouse Entrez Gene: 317260 Rat Omim: 300061 Human SwissProt: Q14202 Human SwissProt: Q9JLM4 Mouse 锌指蛋白ZMYM3抗体Unigene: 522684 Human Unigene: 23458 Mouse Unigene: 92967 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白ZMYM3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:发育生物学 转录调节因子 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid