锌指蛋白279抗体
规格：1mg/1ml
英文名： SUHW2/ZNF279
别名： 5''OY11.1; D87009.C22.3; SUHW2; Suppressor of hairy wing homolog 2; Z280B_HUMAN; Zinc finger protein 279; Zinc finger protein 280B; Zinc finger protein 632; ZNF279; ZNF280B; ZNF632.
分子量： 62kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SUHW2/ZN
交叉反应：Human, Mouse, Dog, Pig, Cow, Rabbit, Sheep, Cat,
细胞定位：细胞核
锌指蛋白279抗体产品介绍：background: The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, 锌指蛋白279抗体but only one of them is protein-coding. [provided by RefSeq, Jan 2015] Function: May function as a transcription factor. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 4 锌指蛋白279抗体C2H2-type zinc fingers. Database links: Entrez Gene: 140883 Human Entrez Gene: 294343 Rat SwissProt: Q86YH2 Human Unigene: 43834 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白279抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 转录调节因子 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid