G蛋白偶联受体7抗体
规格：1mg/1ml
英文名： GPR7
别名： GPCR GPR7; G protein coupled receptor 7; g protein coupled receptor gpr7; GPR7; MGC129755; Neuropeptides B and W receptor 1; Neuropeptides B/W receptor 1; Neuropeptides B/W receptor type 1; NPB and NP
分子量： 59kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GPR7
交叉反应：Human, Mouse,
细胞定位：
G蛋白偶联受体7抗体产品介绍：background: The two G protein-coupled receptors GPR7 and GPR8 display high similarity to each other. They both show high expression in brain and in particular in hypothalamus, and have been characterized as receptors for neuropeptide W (NPW) and neuropeptide B (NPB). In response to NPW and NPB, they play a role in the regulation of feeding behavior. GPR7 deficient mice develop an *****-onset obese phenotype that progressively worsens with age and is exacerbated when fed a high-fat diet. The genes encoding human GPR7 and GPR8 map to chromosomes 10q11.2-q21.1 and 10q13.3, respectively. Function: GPR7 interacts specifically with a number of opioid ligands. It is a receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals, and has a higher affinity for neuropeptide B. It has been reported in brain, mainly cerebellum and frontal cortex, and in the pituitaryG蛋白偶联受体7抗体 (O'Dowd et al., 1995). The mouse ortholog of GPR7 was shown by in situ hybridization to be expressed in discrete nuclei of brain, namely suprachiasmatic, arcuate, and ventromedial nuclei of hypothalamus. Subcellular Location: Cell membrane; Multipass membrane protein. Gene ID: 10936 Database links: Entrez Gene: 428544 Chicken Entrez Gene: 539470 Cow Entrez Gene: 101130191 Gorilla Entrez Gene: 100066961 Horse Entrez Gene: 10936 Human Entrez Gene: 237716 Mouse Entrez Gene: 100517153 Pig Entrez Gene: 100347723 Rabbit Entrez Gene: 4G蛋白偶联受体7抗体98434 Rat Omim: 606704 Human SwissProt: O95800 Human SwissProt: Q6X632 Mouse Unigene: 40763 Human Unigene: 338361 Mouse Unigene: 484157 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid