胸腺TESPA1蛋白抗体
规格：1mg/1ml
英文名： TESPA1
别名： HSPC257; 5830405N20Rik; TESP1_HUMAN; KIAA0748; Protein TESPA1; TESPA1 – thymocyte expressed, positive selection associated 1; TESPA1; thymocyte expressed, positive selection associated 1; Uncharacteri
分子量： 59kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TESPA1
交叉反应：Human, Rabbit,
细胞定位：细胞浆
胸腺TESPA1蛋白抗体产品介绍：Function: Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release and mitochondrial Ca2+ uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment. Subunit: Interacts with PLCG1 and GRB2; the association is increased with 胸腺TESPA1蛋白抗体prolonged stimulation of the TCR and may facilitate the assembly of the LAT signalosome. Interacts with ITPR1. Also interacts with ITPR3 (By similarity). Interacts with HSPA9. Subcellular Location: Cytoplasm. Endoplasmic reticulum membrane. Post-translational modifications: May be phosphorylated in response to store-operated Ca(+2) entry. Gene ID: 9840 Database links: Entrez Gene: 9840 Human SwissProt: 胸腺TESPA1蛋白抗体A2RU30 Human Unigene: 33187 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胸腺TESPA1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid