GRAM结构域蛋白2抗体
规格:1mg/1ml
英文名: GRAMD2
别名: GRAM domain containing 2; GRAM domain containing protein 2; GRAMD 2; GRAM2_HUMAN.
分子量: 40kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GRAMD2
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
细胞定位:细胞膜
GRAM结构域蛋白2抗体产品介绍:background: GRAMD2 is a 354 amino acid single-pass membrane protein that contains one GRAM domain and is encoded by a gene that maps to human chromosome 15q23. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or GRAM结构域蛋白2抗体complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Similarity: Contains 1 GRAM domain. Database links:GRAM结构域蛋白2抗体 UniProtKB/Swiss-Prot: Q8IUY3.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GRAM结构域蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid