Ten-eleven转运基因1蛋白抗体
规格：1mg/1ml
英文名： TET1
别名： Leukemia associated protein with a CXXC domain; CXXC 6; CXXC finger 6; CXXC type zinc finger protein 6; CXXC-type zinc finger protein 6; CXXC6; KIAA1676; LCX; Leukemia-associated protein with a CXXC d
分子量： 235kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TET1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核
Ten-eleven转运基因1蛋白抗体产品介绍：background: TET1 (tet oncogene 1), also known as LCX or CXXC6, is a 2,136 amino acid protein that localizes to the nucleus and contains one CXXC-type zinc finger. Expressed in ***** ovary, thymus and skeletal muscle and also present in fetal lung, heart and brain, TET1 is thought to play a role in the development of fetal organs and may also be involvement in the pathoegenesis and metastasis of acute myeloid leukemia (AML). The gene encoding TET1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, Ten-eleven转运基因1蛋白抗体multiple endocrine neoplasia type 2 and porphyria. Subunit: Interacts with SIN3A; recruits the transcriptional co-repressor SIN3A to gene promoters. Subcellular Location: Nucleus. Tissue Specificity: Expressed in fetal heart, lung and brain, and in ***** skeletal muscle, thymus and ovary. Similarity: Belongs to the TET family. Contains 1 CXXC-type zinc finger. Gene ID: 80312 Database links: Entrez Gene: 80312 Ten-eleven转运基因1蛋白抗体Human Entrez Gene: 52463 Mouse Entrez Gene: 309902 Rat Omim: 607790 Human SwissProt: Q8NFU7 Human SwissProt: Q3URK3 Mouse Unigene: 567594 Human Unigene: 708977 Human Unigene: 17774 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产Ten-eleven转运基因1蛋白抗体品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 干细胞 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid