前列腺素E受体蛋白4抗体
规格:1mg/1ml
英文名: EP4
别名: EP 4; EP4; EP-4; EP4R; MGC126583; PE2R4_HUMAN; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostaglandin E receptor 4; Prostaglandin E receptor 4 subtype EP4; Prostaglandin E2 receptor; Prost
分子量: 53kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human EP4R/Pro
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位:细胞膜
前列腺素E受体蛋白4抗体产品介绍:background: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. Function: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle.前列腺素E受体蛋白4抗体May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. Subunit: Interacts with FEM1A. Subcellular Location: Cell membrane. Tissue Specificity: High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle. Post-translational modifications: Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention. Similarity: Belongs to the 前列腺素E受体蛋白4抗体G-protein coupled receptor 1 family. Database links: UniProtKB/Swiss-Prot: P35408.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
前列腺素E受体蛋白4抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:信号转导 G蛋白偶联受体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid