RFTN2蛋白抗体
规格:1mg/1ml
英文名: RFTN2
别名: Raft-linking protein 2; Raftlin-2; Rftn2; RFTN2_HUMAN.
分子量: 56kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RFTN2
交叉反应:Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep,
细胞定位:细胞膜
RFTN2蛋白抗体产品介绍:background: Membrane microdomains known as lipid rafts are implicated in B-cell activation during B-cell receptor (BCR) signal initiation. Raftlin-2, also designated RFTN2 (raftlin family member 2) or raft-linking protein 2, is a 501 amino acid cell membrane protein that is essential for raft cell assembly and maintenance. A lipid anchor protein, Raftlin-2 belongs to the raftlin family and is encoded by a gene that maps to human chromosome 2q33.1 and mouse chromosome 1 C1.2. Human chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome.RFTN2蛋白抗体 A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Subcellular Location: Cell membrane; Lipid-anchor (By similarity).RFTN2蛋白抗体 Similarity: Belongs to the raftlin family. Database links: UniProtKB/Swiss-Prot: Q52LD8.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RFTN2蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid