膜相关磷脂转运蛋白抗体
规格：1mg/1ml
英文名： NIR1
别名： membrane-associated 3; CORD5; Membrane associated phosphatidylinositol transfer protein 3; Membrane-associated phosphatidylinositol transfer protein 3; NIR 1; NIR-1; NIR1; Phosphatidylinositol transfe
分子量： 106kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NIR1/RDG
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse,
细胞定位：细胞膜
膜相关磷脂转运蛋白抗体产品介绍：background: Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions. Involvement in disease: Defects in PITPNM3 are the cause of cone-rod dystrophy type 5 (CORD5) . CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. Function: Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions. Subunit: Interacts with PTK2B via its C-terminus. Subcellular Location: Endomembrane system; Peripheral membrane protein Tissue Specificity: Detected in brain and spleen, and at low levels in ovary. DISEASE: Defects in PITPNM3 are the cause of cone-rod dystrophy type 5 (CORD5) [MIM:600977].膜相关磷脂转运蛋白抗体 CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa. Similarity: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily膜相关磷脂转运蛋白抗体. Contains 1 DDHD domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
膜相关磷脂转运蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 信号转导 转录调节因子 转运蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid