F-box蛋白家族FBXO18抗体
规格：1mg/1ml
英文名： FBXO18
别名： Fbx18; FLJ14590; MGC131916; MGC141935; MGC141937; F box DNA helicase 1; F box only protein 18; F box protein, helicase, 18; F-box only protein 18, F-box DNA helicase 1; FBH1; FBX18_HUMAN.
分子量： 118kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FBXO18
交叉反应：Human, Mouse, Rat, Dog, Horse,
细胞定位：细胞核
F-box蛋白家族FBXO18抗体产品介绍：background: FBXO18 belongs to the F-box protein family, whose members share the F-box, an approximately 40 amino acid motif. It has both DNA-dependent ATPase and DNA unwinding activities. FBXO18 is a 1,043 amino acid protein encoded by the human gene FBXO18. FBXO18 belongs to the helicase family (UvrD subfamily) and contains one F-box domain. This nuclear protein is a DNA-dependent ATPase that unwinds double-stranded DNA in a 3' to 5' direction. FBXO18 also recognizes and binds to a variety of phosphorylated proteins and promotes their ubiquitination and degradation. It also interacts with Skp1 in the SCF E3 ubiquitin ligase complex consisting of Skp1, CUL-1, Rbx1 and FBXO18. Function: DNA-dependent ATPase. Unwinds double-stranded DNA in a 3' to 5' direction. Probably F-box蛋白家族FBXO18抗体recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Subunit: Part of a SCF E3 ubiquitin ligase complex consisting of SKP1, CUL1, RBX1 and FBXO18. Interacts with SKP1. Subcellular Location: Nuclear Similarity: Belongs to the helicase family. UvrD subfamily. Contains 1 F-box domain. Gene ID: 84893 Database links: Entrez Gene: 84893 Human GenBank:F-box蛋白家族FBXO18抗体 BC113377 Human Omim: 607222 Human SwissProt: Q8NFZ0 Human Unigene: 498543 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
F-box蛋白家族FBXO18抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid