F-box蛋白相关蛋白33抗体
规格:1mg/1ml
英文名: FBXO33
别名: F box only protein 33; Fbx 33; Fbx-33; Fbx33; FBX33_HUMAN.
分子量: 63kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FBXO33
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:
F-box蛋白相关蛋白33抗体产品介绍:background: Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin and F-box proteins act as protein-ubiquitin ligases and mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Function: Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins.F-box蛋白相关蛋白33抗体 Recognizes YBX1 (By similarity). Subunit: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO33) formed of CUL1, SKP1, RBX1 and FBXO33. Interacts via its N-terminus with YBX1 CSD domain. Directly interactsF-box蛋白相关蛋白33抗体 with SKP1 and CUL1 (By similarity). Similarity: Contains 1 F-box domain. Database links: UniProtKB/Swiss-Prot: Q7Z6M2.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
F-box蛋白相关蛋白33抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid