半乳糖凝集素12抗体
规格：1mg/1ml
英文名： Galectin 12
别名： Galectin related inhibitor of proliferation; galectin-12; GRIP1; Lectin galactoside binding soluble 12 (galectin 12); LEG12_HUMAN.
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Galectin
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
半乳糖凝集素12抗体产品介绍：background: Galectin-12, also designated galectin-related inhibitor of proliferation 1 in mouse, is a 314 amino acid protein encoded by the human gene LGALS12. Galectin-12 is a member of the galectin family consisting of b-galactoside-binding proteins with conserved carbohydrate recognition domains. Galectin-12 binds lactose and may participate in the apoptosis of adipocytes. This protein is preferentially expressed in peripheral blood leukocytes and adipocytes. Galectin-12 is induced by cell cycle block at the G1 phase and causes G1 arrest when overexpressed. The galectin-12 gene is expressed in mouse preadipo-cytes and is upregulated when preadipocytes半乳糖凝集素12抗体 undergo cell cycle arrest, concomitant with acquisition of the competence to undergo differentiation in response to adipogenic hormone stimulation. Galectin-12 is an adipocyte-expressed protein which is downregulated by various insulin resistance-inducing hormones. As a result, galectin-12 may play a role in the pathogenesis of insulin resistance. Function: Binds lactose. May participate in the apoptosis of adipocytes. Subcellular Location: Nucleus. Tissue Specificity: Not widely expressed. Predominantly expressed in adipose tissue. Similarity: Contains 2 galectin半乳糖凝集素12抗体 domains. Database links: UniProtKB/Swiss-Prot: Q96DT0.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
半乳糖凝集素12抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学 糖尿病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid