羟基酰谷胱甘肽水解酶样蛋白抗体
规格：1mg/1ml
英文名： HAGHL
别名： HAGHL; HAGHL_HUMAN; Hydroxyacylglutathione hydrolase-like; Hydroxyacylglutathione hydrolase-like protein.
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HAGHL
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆
羟基酰谷胱甘肽水解酶样蛋白抗体产品介绍：background: The hydroxyacylglutathione hydrolase-like protein (HAGHL) is a 290 amino acid protein that belongs to the glyoxalase II family. HAGHL binds two zinc ions per subunit and acts as a hydrolase on ester bonds. The gene encoding HAGHL maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with羟基酰谷胱甘肽水解酶样蛋白抗体 systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. Function: Hydroxyacylglutathione hydrolase (HAGH) is a thiolesterase which hydrolyses S-lactoyl-glutathione to reduced glutathione and D-lactate. Subcellular Location: Cytoplasmic and Mitochondrial Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. Database links: UniProtKB/Swiss-Prot: Q6PII5.1 Important Note: This 羟基酰谷胱甘肽水解酶样蛋白抗体product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 克罗恩病(节段性肠炎)Crohn’s disease(segmental enteritis”,曾称:克隆病)的研究。
羟基酰谷胱甘肽水解酶样蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 信号转导 Alzheimer's
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid