FbxW2蛋白抗体
规格：1mg/1ml
英文名： FbxW2
别名： F box and WD 40 domain containing protein 2; F box and WD repeat domain containing 2; F Box and WD40 Domain Protein 2; F box/WD repeat containing protein 2; FBW 2; FBW2; FBXW 2; Fwd2; Md6; Protein MD6
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FbxW2
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
FbxW2蛋白抗体细胞定位：细胞核
产品介绍：background: F box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F box proteins have been shown to be critical for the ubiquitin mediated degradation of cellular regulatory proteins. In fact, F box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F box proteins. A large family of mammalian F box proteins has recently been FbxW2蛋白抗体identified and classified into three groups based on the presence of either the WD 40 repeats, the leucine rich repeats, or the presence or absence of other protein protein interacting domains. The FBXW2 gene product, the second identified member of the FbxW2蛋白抗体F box gene family, contains multiple WD 40 repeats. Subunit: Directly interacts with SKP1 and CUL1. Subcellular Location: Nuclear Similarity: Contains 1 F-box domain. Contains 4 WD repeats. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产FbxW2蛋白抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid