BTB/POZ结构域蛋白10抗体
规格：1mg/1ml
英文名： BTBD10
别名： BTB (broad complex tramtrack and bric a brac pox virus and zinc finger) domain containing protein 10 ; BTB (POZ) domain containing 10; BTB domain containing 10; BTB/POZ domain-containing protein 10; G
分子量： 54kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BTBD10
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep,
细胞定位：细胞核
BTB/POZ结构域蛋白10抗体产品介绍：background: The BTB (broad-complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD10 (BTB (POZ) domain containing 10), also known as GMRP1, is a ubiquitously expressed nuclear protein found at highest levels in ***** testis, brain and small intestine and weakly expressed in colon, lung, liver, kidney, spleen,pancreas, thymus, prostate, heart and BTB/POZ结构域蛋白10抗体ovary. Down-regulated in glioma, BTBD10 binds PP2A (protein phosphatase 2A) to inhibit dephosphorylation of Akts and is suggested to be a suppressor of cell death as well as an enhancer of cell growth. BTBD10 contains one BTB (POZ) domain and is encoded by a gene mapping to human chromosome 11p15.2. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitously expressed. Highly expressed in BTB/POZ结构域蛋白10抗体***** brain, testis and small intestine and weakly expressed in the heart, lung, liver, kidney, pancreas, spleen, thymus, prostate, ovary and colon. Down-regulated in glioma. Similarity: Contains 1 BTB (POZ) domain. Database links: UniProtKB/Swiss-Prot: Q9BSF8.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产BTB/POZ结构域蛋白10抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid
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