脑胶质瘤发病相关蛋白2抗体
规格：1mg/1ml
英文名： GLIPR2
别名： GAPR 1; GAPR-1; GAPR1_HUMAN; GLI pathogenesis related 2; Glioma pathogenesis related protein 2; Glioma pathogenesis-related protein 2; GliPR 2; GLIPR2; Golgi associated plant pathogenesis related prot
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GLIPR2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
脑胶质瘤发病相关蛋白2抗体产品介绍：background: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged脑胶质瘤发病相关蛋白2抗体 lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis. Subunit: Homodimer.脑胶质瘤发病相关蛋白2抗体 Interacts with CAV1. Subcellular Location: Golgi apparatus membrane. Binds lipid-enriched microdomains of Golgi membranes not only by ionic interactions but also through the myristate. Tissue Specificity: Highest expression in lung and peripheral leukocytes, and minor expression in liver and kidney. Similarity: Belongs to the CRISP family. Database links: UniProtKB/Swiss-Prot: Q9H4G4.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑胶质瘤发病相关蛋白2抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid