泛素蛋白连接酶E3抗体
规格：1mg/1ml
英文名： UBE2E3
别名： Homologous to yeast UBC4/5; UB2E3_HUMAN; UBC E4; Ubc M2; UBC4/5 homolog; UBCE 4; UBCE4; UBCH 9; UBCH9; UbcM2; UBE2 E3; UBE2E3; Ubiquitin carrier protein; Ubiquitin carrier protein E3; Ubiquitin conjug
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human UBE2E3
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
细胞定位：细胞核 细胞浆
泛素蛋白连接酶E3抗体产品介绍：background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the 泛素蛋白连接酶E3抗体regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. Subunit: The ubiquitin-loaded form interacts specifically with importin-11 (IPO11), leading to its import into the nucleus (By similarity). Interacts with NEDD4L. Subcellular泛素蛋白连接酶E3抗体 Location: Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner. Tissue Specificity: Ubiquitously expressed at low levels. Highly expressed in skeletal muscle. Similarity: Belongs to the ubiquitin-conjugating enzyme family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
泛素蛋白连接酶E3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid