KLHDC8A蛋白抗体
规格：1mg/1ml
英文名： KLHDC8A
别名： Kelch domain containing 8A; Kelch domain containing protein 8A; KLHDC 8A; MGC19056; RGD1305132; A630065K24Rik; FLJ10748; KLD8A_HUMAN.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KLHDC8A
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit,
细胞定位：
KLHDC8A蛋白抗体产品介绍：background: Kelch domain-containing protein 8A (KLHDC8A) is a 350 amino acid protein. KLHDC8A contains seven kelch repeats, each of which is an approximately 50 amino acid long conserved region that forms a tertiary structure beta-propeller. The gene that encodes KLHDC8A is located on chromosome 1, which is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria isKLHDC8A蛋白抗体 associated with the LMNA gene which encodes Lamin A. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. Similarity: Contains 7 Kelch repeats. Database links: UniProtKB/Swiss-Prot: Q8IYD2.2 Important Note: This product as supplied is intended for KLHDC8A蛋白抗体research use only, not for use in human, therapeutic or diagnostic applications.
KLHDC8A蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid