RAS癌基因家族蛋白RAB40A抗体
规格：1mg/1ml
英文名： RAB40A
别名： Protein Rar 2; RAB40A, member RAS oncogene family; Rar 2; RAR2A; Ras related protein Rab 40A; SOCS box containing protein RAR2A; RB40A_HUMAN.
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RAB40A
交叉反应：Human,
细胞定位：细胞浆 细胞膜
RAS癌基因家族蛋白RAB40A抗体产品介绍：background: The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 40A, Rab 40B and Rab 40C each contain one SOCS box domain and are members of the Rab subfamily of GTPases. Localized to the cytoplasmic side of the cell membrane, Rab 40A, Rab 40B and Rab 40C are thought to function as substrate-recognition components of a RAS癌基因家族蛋白RAB40A抗体SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that functions to mediate the degradation of target proteins. Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Subcellular Location: RAS癌基因家族蛋白RAB40A抗体Cell membrane; Lipid anchor; Cytoplasmic side (Potential). Similarity: Belongs to the small GTPase superfamily. Rab family. Contains 1 SOCS box domain. Database links: UniProtKB/Swiss-Prot: Q8WXH6.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RAS癌基因家族蛋白RAB40A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid