羧肽酶X(M14家族1)抗体
规格:1mg/1ml
英文名: CPXM
别名: Carboxypeptidase X (M14 family) member 1; Carboxypeptidase X member 1; CPX 1; CPX1; CPXM 1; CPXM1; Metallocarboxypeptidase CPX 1; Probable carboxypeptidase X1; CPXM1_HUMAN.
分子量: 80kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CPXM
交叉反应:Human, Mouse, Rat,
细胞定位:分泌型蛋白
羧肽酶X(M14家族1)抗体产品介绍:background: CPXM (carboxypeptidase X, member 1) belongs to the peptidase M14 family. However, no carboxypeptidase activity has yet been detected. It may be involved in cell-cell interactions.Members of the M14 metallocarboxypeptidase protein family serve many diverse functions and are divided into three subfamilies based on structure, function and amino acid sequence similarity. Belonging to the N/E subfamily, CPXM (metallocarboxypeptidase CPX-1) is a 734 amino acid protein that contains a F5/8 type C domain and likely binds one zinc ion per subunit. Most members of the N/E subfamily contain several domains, including an active carboxypeptidase domain and signal peptide, and are thought to function mostly in protein-protein interactions and/or protein-membrane interactions, thereby 羧肽酶X(M14家族1)抗体targeting the protein to specific locations within the secretory pathway. CPXM is a unique member of this subfamily in that it does not appear to exhibit any enzymatic activity due to lack of several active-site residues that are present in the catalytic domain of other members of the N/E subfamily. Studies showing that CPXM expression is regulated during osteoclastogenesis suggest that CPXM may play a role in osteoclast differentiation. There are two isoforms of CPXM which are a result of alternative splicing events. Function: May be involved in cell-cell interactions. No羧肽酶X(M14家族1)抗体 carboxypeptidase activity was found yet (By similarity). Subcellular Location: Secreted (By similarity). Similarity: Belongs to the peptidase M14 family. Contains 1 F5/8 type C domain. Database links: UniProtKB/Swiss-Prot: Q96SM3.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产羧肽酶X(M14家族1)抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid